Pathomorphological characteristic of IgG4-related diseases
نویسندگان
چکیده
منابع مشابه
Organ Correlation in IgG4-Related Diseases
IgG4-related disease (IgG4-RD) is a potentially multiorgan disorder. In this study, clinical and serological features from 132 IgG4-RD patients were compared about organ correlations. Underlying pathologies comprised autoimmune pancreatitis (AIP) in 85 cases, IgG4-related sclerosing cholangitis (IgG4-SC) in 12, IgG4-related sialadenitis (IgG4-SIA) in 56, IgG4-related dacryoadenitis (IgG4-DAC) i...
متن کاملAutoimmune pancreatitis and IgG4-related systemic diseases.
Autoimmune pancreatitis (AIP) is a rare form of chronic pancreatitis that is characterized by lymphoplasmacytic infiltrate, storiform fibrosis, obliterative phlebitis, and increased IgG4(+) plasma cells. Serum IgG4 levels usually are elevated. Patients with AIP frequently have disease affecting other organs or sites; these tissues show similar histologic changes, including increased IgG4(+) pla...
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Currently, Ormond's disease is classified among IgG4-associated diseases. Its clinical manifestation varies and is characterized by the presence of fibrous retroperitoneal tissue that often affects the ureters or abdominal aorta and iliac arteries. We present a unique case of the polycystic form of Ormond's disease, imitating tumour in the retroperitoneal space. At the time of diagnosis, the di...
متن کاملHistopathological Diagnostic Value of the IgG4+/IgG+ Ratio of Plasmacytic Infiltration for IgG4-Related Diseases
This article aims to perform a meta-analysis to evaluate the diagnostic value of the immunoglobulin G (IgG)4/IgG ratio of plasmacytic infiltration for IgG4-related diseases.Four databases-EMBASE, ISI Web of Knowledge, PubMed, and the Cochrane Library-were systematically searched. Approximately 200 participants from several studies were included in this research. STATA 11.2 software (Stata Corpo...
متن کاملIgG4 (IgG4-RD) related diseases, with a horizon not limited to Mikulicz's disease.
The IgG4-RD is characterized by pseudotumoral inflammatory lesions caused by lymphoplasmocytic infiltration of IgG4+ cells and elevated serum IgG4. For decades, Mikulicz’s disease and Sjögren’s syndrome were considered identical conditions.1–5 IgG1 immunoglobulin is most prevalent (>50%) and the IgG4 variety constitutes less than 5%. IgG4 has disulfide bonds linking the heavy chains unsteadily,...
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ژورنال
عنوان ژورنال: Pathologia
سال: 2016
ISSN: 2306-8027
DOI: 10.14739/2310-1237.2016.2.81051